Job Description

Guardant Health is a leading precision oncology company focused on helping conquer cancer globally through use of its proprietary tests, vast data sets and advanced analytics. The Guardant Health oncology platform leverages capabilities to drive commercial adoption, improve patient clinical outcomes and lower healthcare costs across all stages of the cancer care continuum. Guardant Health has commercially launched Guardant360®, Guardant360 CDx, Guardant360 TissueNext™, Guardant360 Response™, and GuardantOMNI® tests for advanced stage cancer patients, and Guardant Reveal™ for early-stage cancer patients. The Guardant Health screening portfolio, including the Shield™ test, aims to address the needs of individuals eligible for cancer screening.

Job Description

Are you a strategic thinker with a passion for solving revenue cycle challenges? Do you want to be part of an organization that is conquering cancer with new diagnostic products? Join us as a Revenue Cycle Optimization Manager and play a pivotal role in reshaping how we deliver financial performance and operational excellence. In this high-impact leadership position, you’ll drive innovation across the entire revenue cycle using data and process improvement techniques. If you're ready to lead cross-functional initiatives, reduce inefficiencies, and make a difference in the future of cancer treatment, we want to hear from you!

The Revenue Cycle Optimization Manager is a key leader responsible for identifying, developing, and implementing strategic initiatives that drive operational efficiency and reimbursement effectiveness across all functions of the healthcare revenue cycle. This role will focus on continuous improvement within reimbursement operations, including prior authorization, billing, coding, claims follow-up, and collections.

The ideal candidate brings a deep understanding of healthcare revenue cycle management combined with proven experience applying process improvement methodologies (e.g., Lean, Kaizen, Six Sigma) to achieve measurable gains in financial performance, reduce denials, and streamline workflows. This role collaborates cross-functionally to eliminate bottlenecks, strengthen compliance, and improve the end-to-end revenue cycle experience for both patients and providers.

• Collaborate across reimbursement teams (billing, prior auth, coding, A/R) to assess processes and implement improvements that accelerate revenue realization and reduce claim denials.
• Develop and execute targeted process improvement initiatives that optimize key revenue cycle metrics, such as Days in A/R, first-pass resolution rate, and cash collections.
• Lead root cause analysis and performance audits to identify inefficiencies, reduce rework, and improve reimbursement timelines and payer compliance.
• Build and manage a framework for continuous quality improvement, leveraging Lean, Six Sigma, or Kaizen techniques to establish standard workflows and operational excellence.
• Provide guidance and hands-on support to revenue cycle teams, mentoring staff in improvement methodology and project execution.
• Monitor and report on performance KPIs, developing dashboards and tracking mechanisms to evaluate initiative impact and sustain improvements.
• Partner with cross-functional teams in Client Services, Payer Relations, Finance, and IT to align process improvements with broader business and system initiatives.
• Stay current with industry trends, payer changes, and regulatory requirements to proactively adapt reimbursement strategies.

Qualifications

• Bachelor's degree required; Master's degree preferred.
• Minimum of 5 years of experience in healthcare revenue cycle operations, with a focus on reimbursement, billing, or claims management.
• Proven success implementing process improvement frameworks (Lean, Six Sigma, Kaizen) to increase operational efficiency and financial outcomes.
• Strong knowledge of healthcare reimbursement processes, payer requirements, and RCM metrics (e.g., DSO, denial rate, net collections).
• PMP or Lean Six Sigma certification preferred.
• Exceptional analytical and problem-solving skills; advanced proficiency in data tools (e.g., Excel, Tableau, or similar platforms).
• Strong interpersonal and leadership skills with the ability to influence cross-functional teams and drive change.
• Clear, effective communication with internal stakeholders, including operations, clinical teams, and executive leadership.

Additional Information

Hybrid Work Model : At Guardant Health, we have defined days for in-person/onsite collaboration and work-from-home days for individual-focused time. All U.S. employees who live within 50 miles of a Guardant facility will be required to be onsite on Mondays, Tuesdays, and Thursdays. We have found aligning our scheduled in-office days allows our teams to do the best work and creates the focused thinking time our innovative work requires. At Guardant, our work model has created flexibility for better work-life balance while keeping teams connected to advance our science for our patients.

For positions based in Palo Alto, CA or Redwood City, CA, the base salary range for this full-time position is $133,900 to $180,810 The range does not include benefits, and if applicable, bonus, commission, or equity.

Within the range, individual pay is determined by work location and additional factors, including, but not limited to, job-related skills, experience, and relevant education or training. If you are selected to move forward, the recruiting team will provide details specific to the factors above.

Employee may be required to lift routine office supplies and use office equipment. Majority of the work is performed in a desk/office environment; however, there may be exposure to high noise levels, fumes, and biohazard material in the laboratory environment. Ability to sit for extended periods of time.

Guardant Health is committed to providing reasonable accommodations in our hiring processes for candidates with disabilities, long-term conditions, mental health conditions, or sincerely held religious beliefs. If you need support, please reach out to  Peopleteam@guardanthealth.com

Guardant Health is an Equal Opportunity Employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, or protected veteran status and will not be discriminated against on the basis of disability.

All your information will be kept confidential according to EEO guidelines.

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